FOREWORD 21 



in American Medicine for October and November, 1914, under 

 title of the Proteomorphic Theory. I made the first specific ther- 

 apeutic application of the theory in detail to the treatment of a 

 particular malady, with the explicit suggestion that the non- 

 specific proteins would be applicable in combating all types of 

 protein toxaemias, including bacterial diseases, in the New York 

 Medical Journal of October 2, 1915. A more elaborate explica- 

 tion was given, with detailed study of the blood modifications 

 attending the use of the Proteals, in a Monograph of 126 pages 

 bearing the title The Proteal Treatment of Cancer and Allied 

 Conditions, issued December 1, 1916. The name Proteal was 

 first introduced (together with the name Proteantigen as a fam- 

 ily name for all proteins used as antigens, including Serums and 

 Vaccines as well as Proteals), and the principle that a single 

 protein or combination of proteins must not be depended on to 

 secure optimum results in the majority of cases was first pub- 

 licly enunciated, in this Monograph, which bore the sub-title A 

 Practical Study of a New Therapeutic Principle as Interpreted 

 in the Light of the Proteomorphic Theory. 



The practical results of Proteal therapy in my own hands 

 and in the hands of several hundred associated physicians have 

 been of a character calculated to arouse enthusiasm. I made a 

 statistical analysis of 766 cases, treated by 152 physicians, in a 

 preliminary report published in the New York Medical Journal 

 of November 13, 1915. A considerable body of new evidence 

 was available when my Monograph above cited was published a 

 little over a year later, but this work was largely devoted to the 

 theory of Proteal action, with especial reference to the modi- 

 fication of blood conditions, to which I had devoted assiduous 

 attention, believing that to be the crux of the entire matter. 



During the summer of 1917, in the course of a long lecture 

 tour in the West, I delivered about one hundred addresses on 

 Proteal Therapy before gatherings of medical men, including sev- 

 eral County Medical Societies. The interest aroused is evidenced 

 in the subsequent use of the Proteals by a large number of phy- 

 sicians who heard these addresses. The co-operation of these 

 practitioners has been a valuable asset in further tending to es- 

 tablish the applications of the Proteals in a variety of maladies 

 with which previous experience had been limited including 

 asthma and tuberculosis. The joint experience of this group of 

 physicians and of others previously interested has served to for- 

 tify and extend my personal observations. 



OTHER NON-SPECIFIC PROTEINS 



It should be clearly understood, however, that, whereas I make 

 constant specific reference to the Proteals, and tell of the defi- 



