CHAPTER IV 

 THE SCIENCE AND ART OF PROTEAL THERAPY 



If the testimony presented in the earlier chapters of this 

 book is accepted as conclusive, it will be understood that the 

 most salient bodily response to the hypodermic administration 

 of proteins has to do with the regeneration of the blood. 



I have observed, as characteristic and almost uniform effects 

 of proteantigen treatment, increase of haemoglobin, increase in 

 numbers and modification in quality of the red corpuscles, and 

 modification of the white corpuscles in the direction of normal 

 numbers, relative decrease of polynuclears, and relative increase 

 of mononuclears, in particular the large mononuclears, and of 

 eosinophiles. 



These modifications of the blood are too conspicuous and too 

 uniform to be considered as accidental. They have been ob- 

 served in a considerable variety of maladies, including simple 

 anaemia, secondary anaemia, pernicious anaemia, Graves' disease, 

 intestinal toxaemia, and other protein toxaemias, rheumatoid 

 arthritis, chronic articular rheumatism, tuberculosis, mastitis, 

 and cancer. The aggregate number of cases under observation 

 is large enough to justify deductions of a somewhat definite 

 character. 



The original studies, and up to the present by far the most 

 comprehensive ones, bearing on this subject have been made by 

 the writer himself or under his immediate personal supervision ; 

 but corroborative testimony as to individual cases has come 

 from many independent sources, telling of observations of physi- 

 cians who have administered the proteal treatment to patients 

 suffering from a variety of maladies. In particular these observa- 

 tions have had to do with the improvement in haemoglobin and 

 the increase of the red blood count; since a good many physi- 

 cians make observation of these matters without taking time 

 to make careful differential leucocyte count. It is hoped that 

 physicians in general will pay more attention in the near future 

 to the blood count in general and the leucocyte count in partic- 

 ular, partly, at least, as a result of the evidence presented in my 

 cancer Monograph and in the present volume. 



Meantime practitioners who have not facilities for careful 

 blood examinations may observe the clinical effects of the use 

 of the new method, which after all is, in the last analysis, the 

 matter of genuine importance. If the patient looks better, feels 

 better, has improved appetite and digestion, sleeps better, gains 



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