THE SCIENCE AND ART OF PROTEAL THERAPY 135 



this patient's blood was examined before treatment, it is found 

 that the leucocytes stained with very blue nuclei, many of them 

 taking the stain very badly. Lymphoidocytes and plasma cells 

 largely took the place of normal cells. There were no normo- 

 blasts, and no platelets. After a week of Proteal treatment, the 

 entire character of the white cells had changed. The record 

 reads: "Polynuclears stained beautifully, with purple nuclei; 

 cytoplasm granular, moderately acidophile. All lymphocytes 

 stained typically. No lymphoidocytes or plasma cells. A very 

 normal collection of white cells, beautifully stained. Numerous 

 big typical large monocytes. Occasional normoblasts, platelets 

 numerous." 



Two weeks later further modifications in the same direction 

 had taken place. The white cells were evenly distributed in the 

 smear, except that a few very large monocytes and myelocytes, 

 owing to their bulk, dragged toward the end. Nuclei took a 

 normal purple stain, the cytoplasm of the polynuclears conspic- 

 uously red-granuled. Platelets were now fairly abundant, and 

 normoblasts absent or extremely rare. 



It is impossible not to associate such modifications of the 

 cells with the marked improvement in clinical symptoms mani- 

 fested by the patient. When one has seen similar modifications 

 take place under Proteal treatment again and again, the belief 

 that there is a causal relation between the administration of the 

 Proteals and the changed blood condition, and that the improved 

 clinical conditions are effects and not accidental concomitants, 

 becomes a firm conviction. 



If the subject to whom the protein extract is administered is, 

 let us say, a patient with cancer of the uterus, associated with 

 pain, a fcetid discharge, and marked cachexia, there is likely to 

 be a very notable modification of symptoms. The pain may 

 largely disappear after two or three treatments; the character 

 of the discharge may be so modified that it becomes watery and 

 inodorous ; and the general physical condition of the patient may 

 be strikingly modified in a favorable direction. As the treatment 

 continues, the neoplasm itself may undergo a conspicuous and 

 unequivocal regression to a greater or less extent. 



Similar modifications may be observed in malignant neoplasms 

 of various types wherever located in the body. There remains, 

 however, the highly interesting question as to how such changes 

 are brought about by the hypodermic administration of small 

 quantities of vegetable proteins. 



MODIFICATIONS OF THE LEUCOCYTE COUNT 



A further clue to the answer is found in the fact that con- 

 spicuous modifications of the leucocyte count no less than of the 



