THE SCIENCE AND ART OF PROTEAL THERAPY 137 



in number so that, after treatment has been continued for a time, 

 they fall within normal limits. Here, for example, is one chart 

 (Case No. 332) in which at the outset the number of neutrophiles 

 was 5,328, and the number of small lymphocytes 2,131 ; these 

 numbers representing in each case an excess above the maximum 

 normal limits, as usually computed. But after treatment had 

 extended over about 90 days, it was observed that the polynu- 

 clears numbered 4,356, and the small lymphocytes 1,824; both 

 these numbers representing a (high) normal count. 



But in the meantime, it should be noted that the large mono- 

 cytes, which at the outset numbered 1,420, had increased to 2,403. 

 The original count is far in excess of the normal (which seldom 

 exceeds 400), and the final count exceeds the maximum normal 

 limits by 600 per cent. The assumption is, according to the pres- 

 ent thesis, that before treatment the large monocytes had been 

 stimulated to excessive production under influence of the disin- 

 tegrated cancer cells; and that the protein treatment effected a 

 further stimulation. 



A similar proportionate increase in the eosinophiles has taken 

 place, there being none noted at all before treatment and the 

 number having risen almost continuously until 356 were noted at 

 the later count, about double the normal maximum limit. 



Whatever the interpretation put upon these facts, it would 

 appear, as already pointed out, that such a super-normal count 

 of large monocytes and eosinophiles constitutes a favorable 

 condition in the organism associated with improved general 

 health of the patient and a tendency to combat the cancer cells 

 effectively. Indeed, I never feel that the desired results are 

 being attained unless this characteristic response is observed. 



Another chart illustrates the same principle in a different way; 

 inasmuch as it was necessary to increase the number of neutro- 

 philes in order to bring them to a high normal limit. It will be 

 observed in this chart (Case No. 369) that at the outset the 

 neutrophiles numbered 4,190 and the small lymphocytes 2,630. 

 At the end of three weeks' treatment, the polynuclears had risen 

 to 4,935, and the small lymphocytes had dropped to 1,410. Here, 

 as before, the final count shows polynuclears and small lympho- 

 cytes within normal limits. 



In the meantime, in this second chart, as in the first, the large 

 monocytes have risen conspicuously; in this case from 1,150 to 

 2,608 ; and the eosinophiles have increased from 213 to 329. The 

 numbers here are substantially in accord with those shown in 

 the other chart. Such close agreement is a matter of coincidence, 

 although the same general principle will be seen reiterated in a 

 large number of cases. 



A striking feature of both these charts is the marked modifi- 



