THE SCIENCE AND ART OF PROTEAL THERAPY 161 



gree beneficial, and that the judicious use of proteantigens may 

 stimulate the blood-forming mechanism to the effective combating 

 of toxins both of bacterial and non-bacterial origin against which 

 no other measure of corresponding efficacy is available. 



I have already presented tables showing that the modifications 

 of the blood count under proteantigen treatment may be, and 

 frequently are, progressive in what I consider the right direction. 

 I am preparing for publication in the new edition of the Mon- 

 ograph more elaborate series of tables in which blood counts of 

 various patients are arranged sequentially as to time; beginning 

 with a series of counts of untreated cases, and going on day by 

 day to cases that have been under treatment for a term of 

 months. For convenience of observation, these cases are ar- 

 ranged in successive groups by ten-day periods. This, it will 

 be understood, is a purely arbitrary division, made merely to 

 give opportunity to classify results and show at a glance the 

 general -effect of treatment given a variety of cases for shorter 

 and longer periods of time. It will be seen that, generally speak- 

 ing, there is a progressive or cumulative effect observable ; that, 

 in other words, cases that have been the longest under treat- 

 ment are, on the average, those that show the most pronounced 

 modification of the blood count in the direction of (a) higher 

 haemoglobin index, (b) increase of red corpuscles, (c) modifica- 

 tion toward the normal of the leucocyte count, with (d) relative 

 increase of mononuclear leucocytes, and in particular marked 

 increase of large mononuclears. 



If these facts are interpreted in the light of the Proteomorphic 

 theory, it appears that the conglomerate group of patients here 

 under consideration have benefited progressively by the prote- 

 antigen treatment, and that those that have been treated more 

 or less regularly for periods of six months, a year, and even 

 two years, are in better condition, as regards their blood count, 

 than those treated for a shorter period. When it is further stated 

 that these patients, observed as to their clinical condition, show 

 a similar status of improvement, the case for the non-toxicity of 

 proteantigens of types herein referred to (chiefly egg albumen, 

 milk albumen, sheep serum, and the Proteals) may be considered 

 to be fairly established. 



I may add, by way of auxiliary evidence, that of the hun- 

 dreds of physicians who have used the Proteals from my labora- 

 tory no one has ever reported a reaction giving occasion for the 

 slightest alarm, much less a lethal effect; whereas testimony to 

 the beneficial effects resulting, seemingly in direct consequence 

 of the administration of the Proteals, has been so nearly unani- 

 mous as to satisfy the most optimistic anticipations. 



