198 THE PROTEOMORPHIC THEORY AND THE NEW MEDICINE 



The patient's physical condition was much better than on the 

 eighth day, but not so good as on the sixth. 



Proteal treatment was continued, in doses of 5 to 10 minims, 

 on alternate days, and the clinical progress of the patient was so 

 conspicuous as to be noticed by all her friends. She spoke of 

 herself as being "quite made over." The distressing giddiness 

 disappeared altogether ; her appetite was good, and she had no 

 nausea or other gastric disturbance ; she slept well, felt cheerful 

 and bouyant, and in general was in a condition that simulated 

 normal health. On the 28th day of the treatment, her blood 

 count showed 4,074,000 red corpuscles of fairly normal appear- 

 ance (totally different in aspect from the original condition), 

 and 7,150 white corpuscles, of which 52 per cent, were polynu- 

 clears, 28 per cent, small lymphocytes, 18.5 per cent, large 

 mononuclears, and 1.5 eosinophiles. The polynuclears stained 

 blue, but their cytoplasm was distinctly acidophile. The mono- 

 nuclears were mostly typical large monocytes, with only a few 

 questionable myelocytes. No normoblasts were seen, but there 

 was a fair number of platelets. Except that the red cells were 

 not quite as numerous as might be desired, this blood picture is 

 in the highest degree satisfactory. 



On the 35th day, the defect in the red corpuscles had been 

 remedied, as these now number 5,328,000. The quality of the 

 red cells was correspondingly satisfactory, being recorded in the 

 main very normal, except that some were small. The white cells 

 now numbered 7,700, with 63.5 per cent, polynuclears, 13.5 per 

 cent, small lymphocytes, 19 per cent, large monocytes, practically 

 all of them large lymphocytes or typical large monocytes, 2 per 

 cent, eosinophiles, and only a negligible number of myelocytes. 

 It is recorded that the polynuclears were of normal appearance 

 with cytoplasm taking acidophile stain moderately, and nuclei 

 staining deeply. Large monocytes and eosinophiles were large 

 and beautifully typical. 



Here it will be noted that the polynuclears were more numer- 

 ous than in the preceding counts (although far short of their 

 original percentage), and that this increase had apparently been 

 made at the expense of the small lymphocytes, the large mononu- 

 clears being more abundant than on any previous occasion. That 

 this blood condition was salutary is evidenced by the fact that 

 the patient's clinical condition continued in the highest degree 

 satisfactory, notwithstanding that she had been for ten days of 

 this period under excessive mental strain owing to the critical 

 illness of a member of her family. It now became necessary 

 for the patient to go to California, and she accomplished the 

 journey without incident, although she would have been utterly 





