THE SCIENCE AND ART OF PROTEAL THERAPY 217 



curious vacuolations or typical modifications of the structure 

 giving a figured appearance. 



All these things, to be sure, may be seen more or less in rela- 

 tively normal blood cells; but the proportion of cells showing 

 such aberrant conditions is very greatly increased in cases of 

 intestinal toxaemia, particularly when associated with rheumatic 

 sequels. One cannot well doubt that there are profound chem- 

 ical changes in both red and white cells of such a subject. 



A typical case recently under treatment is that of a young 

 woman whose clinical symptoms included "general debility," poor 

 circulation associated with cold hands and feet, lack of appe- 

 tite, lassitude and depression, and a tendency to enlargement and 

 pain of the finger joints of "rheumatic" character. 



The blood count showed 3,571,000 red corpuscles of character- 

 istic abnormal quality, and 9,690 white cells of the faint-staining, 

 clumping variety. The polynuclears represented 82.6 per cent., 

 small lymphocytes 9.6 per cent., the large mononuclear 7 per 

 cent., and the eosinophiles 0.6 per cent. 



After three weeks of Proteal treatment (Nos. 37 and 45 in 

 doses of 3 to 6 minims on alternate days), there was marked 

 improvement all along the line in clinical symptoms, including 

 conspicuous change in the patient's appearance and feelings, and 

 the blood count showed more than 6,000,000 red cells which at 

 first seemed normal, but afterward became picturesquely modi- 

 fied along the lines just referred to. The white cells had been 

 reduced to 5,800, and there was most striking modification of 

 the differential count, which now showed 59.5 per cent, poly- 

 nuclears, 26.5 per cent, small lymphocytes, and 14 per cent, large 

 mononuclears. Occasional normoblasts and groups of platelets 

 were now present. A modification of the chemical condition 

 of the whites was suggested in the fact that the nuclei now 

 stained deep purple, the cytoplasm being markedly acidophile. 

 The individual leucocytes were large, and there was not much 

 clumping. 



This patient, obviously, requires a long course of proteal treat- 

 ment to bring about permanent modification of the disturbances 

 of metabolism, but the changes effected in so short a period are 

 striking and gratifying. The case is still under treatment. 



BY WAY OF SUMMARY 



The reader of the Monograph on The Proteal Treatment of 

 Cancer is aware that the theory that underlies my interpretation 

 of most of the phenomena of protein therapy traces a large part 

 of the ills of middle life to disturbances of protein metabolism. 



