THE EVOLUTION OF THE PROTEIN PRINCIPLE 245 



tension of methods was being employed by Klinger in Switzer- 

 land, my associates and I were working quite independently along 

 precisely similar lines, using vegetable proteins for the most part 

 instead of animal proteins, with strikingly analogous results. 



Klinger's results are published in the Korrespondenz-Blatt fiir 

 Schweizer Aerzte, September 23, 1916. A lengthy summary of 

 the article appears in the Journal of the American Medical Asso- 

 ciation for November 4, 1916. No one could fail to note the 

 similarity of the description of Klinger's results with his auto- 

 lysates to my previously published reports of results obtained with 

 vegetable proteins. For example, he says, as condensed in the 

 Journal of the American Medical Association: 



"Quite a number of cases have been reported of complete cures 

 or essential improvement under Autolysate treatment of previous- 

 ly inoperable cancer. In Betrand's case an extensive recurrence 

 of a mammary cancer was completely cured. On suspension of 

 the treatment after several months of daily injunction, the tumor 

 began to grow again. The resumption of growth on suspension 

 of the treatment apparently shows that the cure was not a spon- 

 taneous subsidence of the tumor but was actually the work of the 

 treatment. Such brilliant results are exceptional. But even in 

 the only improved cases the inflammatory infiltration may sub- 

 side and the tumor may cast off necrotic masses, the edge of the 

 ulceration healing over. Cancers bleeding and suppurating pro- 

 fusely may have the bleeding and secretion arrested. The tumor 

 often grows so much smaller that the esophagus or the rectum 

 may become permeable once more. Pains caused by the infiltra- 

 tion subside as this retrogresses. In many cases the growth be- 

 comes operable after a few weeks of Autolysate treatment." 



All this, obviously, might have been written of the effects of 

 administering the vegetable proteins instead of the animal pro- 

 teins of the autolysates. Note also the following: 



"Klinger regards intravenous injection as the most effectual 

 route. There does not seem to be any danger of an anaphylaxis, 

 he says, but sometimes the autolysates seem to lose their power. 

 This can be avoided by changing the material." 



The striking analogy here with what has been pointed out in 

 detail again and again in the present book about wearing out the 

 effect of one Pro teal and changing to another will be obvious to 

 every reader. Even more striking are the analogies suggested by 

 the theoretical explanation offered as to the action of the auto- 

 lysates, as follows: 



"The results of Klinger's own research and experience confirm 

 the possibility of influencing the growth of a tumor by injecting 

 certain products of the breaking down of albumin. These auto- 

 lysates supply the body with ready-made ferment while at the 

 same time exerting a stimulating action on the blood-producing 



