CHAPTER XXX 



NEO-MENDELIAN HEREDITY IN ANIMALS 

 H. H. NEWMAN 



Immediately after the announcement by De Vries in 1900 of the 

 rediscovery of Mendel's paper, zoologists hi Europe and hi America 

 began experiments hi animal breeding with the idea of discovering to 

 what extent Mendel's laws were applicable. It was soon found that 

 the principles of unit characters, dominance, segregation, mono- 

 hybrid, dihybrid, and trihybrid ratios were of practically universal 

 application. A number of Instances of Mendelian heredity hi animals 

 have already been presented hi the preceding chapter and no more 

 simple Mendelian cases need be described. For a considerable period 

 the animal-breeders proceeded no farther hi their analysis of the 

 mechanism of heredity than Mendel had done so many years before. 

 In tune, however, new facts came to light that needed further analysis, 

 and the older Mendelism was superseded by neo-Mendelism. This 

 new phase hi the study of heredity is hi the forefront of interest today. 

 Neo-Mendelian heredity hi plants has already been discussed. It 

 remains for us to present the data on some phases of neo-Mendelism 

 in animals. 



ILLUSTRATIONS OP THE FACTOR HYPOTHESIS 

 THE FACTORIAL ANALYSIS OF COLOR IN MICE 



Miss Durham, after extensive breeding experiments with numer- 

 ous strains of differently colored mice, has been able to show that 

 the appearance of a particular color in an individual mouse is depend- 

 ent upon the presence or absence of several independently inherited 

 factors, evidently represented by genes hi as many different chromo- 

 somes. It seems possible to classify these factors as follows: 

 B= black pigment, which masks chocolate pigment 

 b = absence of B, which gives chocolate 

 7= intensity factor 



i = absence of intensity, or dilution factor 

 C =a complementary color factor acting with P 

 P=SL complementary pigment factor acting with C 

 If either C or P are absent, albino mice result no matter what 

 other color factors may be present. 



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