CONTENTS. 



SECTION I. 

 GENERAL CHARACTERS OF SPIROCH^ETES. 



PAGB 



BIOLOGICAL POSITION OF SPIROCH^ETES - . . n 



MORPHOLOGY OF SPIROCH^TES 16 



Large Spirochaetes 16 



Shape . . . '. = .'... 18 



Movements 19 



Structure 19 



Undulating Membrane 20 



Nucleus 21 



Small Spirochaetes ...*..- 25 



Movements 25 



Structure ..... 26 



VARIABILITY OF FORM 29 



HABITAT 31 



CULTIVATION 31 



MULTIPLICATION AND DEVELOPMENT 33 



Conjugation 37 



Encystment . , . - 38 



Sporulation , 40 



Coccoid Forms 40 



ASSOCIATION WITH OTHER ORGANISMS 42 



PATHOGENICITY 45 



Relapsing Fever . 45 



African Tick Fever 46 



Other Forms of Current Fevers 47 



Syphilis 48 



Yaws (Pian, Frambcesia) 57 



Lymphadenoma 57 



Ulcerative Granuloma 58 



Vincent's Angina 58 



Other Diseases in Man 59 



Diseases of Animals (Fowls, Cattle, Bat, Pig, Mouse) . . 60 



SUMMARY OF PHENOMENA OF PATHOGENICITY OF SPIROCH^TES 62 



