CONTENTS XV 



PART IV. CHEMICAL DYNAMICS IN PROTEIN SYSTEMS 



PAGE 



CHAPTER XV. THE HYDROLYSIS OF THE POLYPEPTIDS 371 



1. The Hydrolysis of Polypeptids by Proteolytic Enzymes 371 



2. The Kinetics of the Hydrolysis of Polypeptids by Proteolytic 



Enzymes 376 



3. The Order in which Amino-acids are Split off from Polypeptids by 



Proteolytic Ferments 385 - 



CHAPTER XVI. THE HYDROLYSIS OF THE PROTEINS 389 



1. The Proteolytic Enzymes as Catalysors 4.389 



2. The Evidence for the Existence of Intermediate Compounds 



between the Proteolytic Ferments and their Substrates 398 



3. The Kinetics of Protein Hydrolysis by Enzymes 400 



4. The Influence of Acid and Alkali upon the Rate of Protein Hy- 



drolysis by Enzymes 410 



5. The Influence of Added Substances upon the Rate of Protein 



Hydrolysis by Enzymes 415 



6. The Action of the Coagulating Ferments, Rennet and Thrombin. 416 



7. The Influence of Temperature upon the Velocity of Protein Hy- 



drolysis 419 - 



CHAPTER XVII. THE ENZYMATIC SYNTHESIS OF PROTEINS 425 ^~ 



1. The Reversion of the Hydrolysis of Proteins by Pepsin and Tryp- 



sin 425 



2. The Probable Nature of the Coaguloses and Plasteins 437 



3. The Chemical Mechanics of the Fermentative Synthesis of Pro- 



teins 439 



4. Reciprocal Catalysis 444 



5. The Influence of Temperature upon the Enzymatic Synthesis 



of Proteins 448 



6. The Thermodynamics of the Enzymatic Hydrolysis and Synthesis 



of Proteins 450 



7. Biological Applications ./fTS^. 452 



[ 

 APPENDIX. THE TECHNIQUE OF ELECTROCHEMICAL MEASUREMENTS 



IN PROTEIN SYSTEMS \ 456 



INDEX OF AUTHORS > x 469 



INDEX OF SUBJECTS 479 



