64 SWINE DISEASES 



interlobular tissue is infiltrated with leukocytes. The 

 liver tissue is soft and friable. Microscopic study of 

 these livers has revealed the fact that in nearly every 

 instance the infiltration leukocytes are practically all 

 eosinophiles. 



Symptoms. Few if any investigations of these 

 cases have been made clinically or at least such have 

 not been reported. The marked interlobular infiltration 

 tends to obstruct the biliary capillaries, causing reab- 

 sorption of bile with accompanying icterus. 



Treatment. The nature of this condition permits 

 of little if any relief by the use of drugs. Providing the 

 proper diet and surroundings are provided, treating the 

 symptoms as they arise is apparently all that can be 

 advised for the relief of this condition. 



Chronic Interstitial Hepatitis (Cirrhosis -Sclerosis) 



Chronic interstitial hepatitis, cirrhosis or sclerosis of 

 the liver, consists of a proliferation of fibrous tissue 

 which damages and ultimately displaces some of the 

 functional liver tissue. The condition is rather common, 

 especially in swine fed upon fermented products, such 

 as distillery waste, or garbage. 



Etiology. This condition is due to injurious chemical 

 agents derived either from the food or from bacterial 

 action, that is, those substances that are capable of 

 producing a mild degree of irritation. Animal para- 

 sites, either by direct mechanical irritation or irritation 

 by eliminated chemicals, also produce chronic inter- 

 stitial hepatitis. The condition, too, may be secondary 

 to other disease processes. 



Lesions. Chronic interstitial hepatitis is essentially 

 a proliferation of fibrous tissue. The fibrous tissue may 

 be produced within the liver lobule, causing an enlarge- 

 ment of the lobules and also of the liver. This type is 

 designated hypertrophic sclerosis of the liver. Such a 

 liver is enlarged, dense, increased in weight, lighter in 

 color, and when cut gives the impression of cutting 

 fibrous tissue. In other instances the proliferation of 



