230 SWINE DISEASES 



lation of a laboratory animal with a small quantity of 

 the brain tissue of the animal in question. 



Treatment. Curative treatment has always been 

 considered futile. Recently the use of quinine has, 

 according to reports, given good results in cases of rabies 

 in dogs. Other investigators have failed to obtain 

 beneficial results from the use of quinine in experimentally 

 inoculated cases of rabies. If valuable animals are 

 known to have been bitten by a rabid dog it may be 

 given the Pasteur treatment and thus the development 

 of the disease prevented. 



Foot and Mouth Disease. (Aphthae Epizooticse) 



This is an acute, infectious, transmissible disease, 

 primarily affecting cattle and sheep. It also affects 

 hogs, goats, more rarely horses, dogs and other animals. 



This disease is quite prevalent in some European 

 countries and it has appeared in the United States on six 

 different occasions: In 1870, 1880, 1884, 1902, 1908 and 

 1914. 



Etiology. Foot-and-mouth disease is produced by 

 one of the so-called filterable viruses, which up to the 

 present time has not been successfully cultivated outside 

 of the animal body. The virus exists especially in the 

 serous fluids of the vesicles in the mouth, from which it 

 gains entrance to the saliva and thus to the soil and food 

 from the salivary secretions. The vesicular lesions are 

 also found on the feet and thus the virus also gains en- 

 trance to soil, bedding and food, from which other animals 

 can easily obtain infection. There appears to be little 

 doubt but what the virus is eliminated from the body in 

 all excretions. The exact length of time the virus will 

 retain its vitality outside of the animal body has not 

 been determined, but it has been observed that infection 

 will persist in buildings that have not been disinfected 

 for several months. Some outbreaks of this disease 

 have been apparently traced to contaminated hay, that 

 had not been in contact with diseased animals for three 

 months or more. Thus infection mav be obtained from 



