GLYCEBOPHOSPHORIC ACID 307 



anaemia, rickets, diabetes, tuberculosis, and of nervous 

 affections associated with lowered vitality. In convales- 

 cence following canine distemper it is especially valuable. 

 Doses for the dog, gr. j. to grs. v. ; in pill or mixed with the 

 food. 



GLYCEROPHOSPHORIC ACID. Glycerophosphates. 



Glycerophosphoric acid may be prepared by heating 

 glycerin with phosphoric acid, and subsequently neutralising 

 the product with calcium carbonate. It is a pale, yellowish, 

 syrupy fluid, with a sour taste, seldom employed medicinally. 

 Its salts, the glyeerophosphates of calcium, iron, potassium, 

 sodium, magnesium, and quinine, are frequently prescribed 

 and are of great value in the treatment of debilitating and 

 nervous diseases. Glycerophosphate of calcium, prepared by 

 heating together bicalcic phosphate, phosphoric acid, and 

 glycerin, is a light white powder, soluble in 20 parts cold 

 water, forming a neutral solution. Recent investigations 

 suggest that this salt merits extended trial in tuberculosis, 

 rickets, and other diseases depending on malnutrition ; and 

 in all cases requiring the administration of a tonic restorative 

 the glycerophosphate is preferable to the phosphate as it is 

 much more easily assimilated. The glyeerophosphates of 

 sodium and potassium are alkaline syrupy liquids which are 

 usually prescribed in combination with other salts . Glyeero- 

 phosphate of quinine is especially indicated in cases associated 

 with indigestion and low fever ; and glycerophosphate of 

 iron, which occurs in greenish-yellow scales, soluble in five 

 parts of cold water promotes nutrition by furnishing 

 phosphoric acid and iron in a very assimilable form. It is 

 an excellent tonic (Kaufmann). Doses of calcium and iron 

 glyeerophosphates, horses, 3*9 5 dogs, grs. v. to grs. xv. 

 per day. Quinine glycerophosphate is prescribed in the 

 same doses as quinine sulphate. Hypodermically, a five 

 per cent, solution of the calcium salt, or a twenty per cent, 

 solution of the sodium salt may be injected in doses of H\v. 

 to 3ij- P er d av m th e dog. Glyphocal emulsion with 

 almond oil (Squire and Sons), containing the glycerophos- 

 phates of calcium, iron, potassium, and sodium, with pepsin 



