398 ACETANILIDE 



hypodermically for local pains. Its haemostatic power is 

 greatly increased by admixture with tannin solution. 



DOSES, etc. Horses take 39- ^ 3i y - '> cattle, 3 n J- to 

 3vi. ; sheep, grs. xxx. to 3*- J dogs, grs. iv. to xx., given in 

 bolus, drench, electuary, or in the drinking water, and 

 repeated as may be required. For hypodermic or in- 

 tratracheal injection in horses the dose is 40 grains 

 dissolved in four drachms of water. As some animals 

 are very susceptible to its depressant effects, it is well 

 to begin with small doses, and repeat twice or thrice 

 daily. 



Acetopyrine, or acetosalicylate of antipyrine, is sometimes 

 employed as a substitute for antipyrine. It is antipyretic 

 and analgesic. It occasions neither gastric nor cardiac 

 disturbance, and does not affect the kidneys. It con- 

 stitutes a good antipyretic without accessory depression of 

 the heart. It promotes the secretion of the pancreas, 

 and, after a time, that of the skin. It has proved beneficial 

 in rheumatism, influenza, and pneumonia, in which it eases 

 pain and lowers temperature. It may be prescribed in 

 doses about one-third less than those of antipyrine. 



ACETANILIDE OR ANTIFBBRIN 



ACETANILIDUM. CH 3 .CO.NH.C 6 H 5 . PHENYL-ACETAMIDE. 

 (Antifebrin is a registered name.) 



Acetanilide, one of the most serviceable of the benzol or 

 aromatic carbon series, is a crystalline substance, prepared 

 by the interaction of glacial acetic acid and aniline. It is 

 colourless, odourless, with a slightly burning taste, oily to 

 the touch, soluble in 190 parts of water, four parts rectified 

 spirit, forty parts glycerin, freely soluble in ether, benzol, 

 and chloroform. 



ACTIONS AND USES. It is antipyretic, sedative, diuretic, 

 and feebly antiseptic. Even in excessive doses it rarely 

 causes toxic symptoms in animals, although in man it is 

 more toxic than antipyrine, and more liable to produce 

 dangerous collapse. It is neither irritant nor nauseous, 

 and has, moreover, the merit of cheapness. Compared 



