404 NAPHTHALOL AND PHENACETIN 



forms Naphthol Camphor, a viscid, non-toxic antiseptic, 

 which, mixed with an equal part of glycerin or olive oil, 

 is used as a dressing for auricular catarrh and small wounds. 

 Doses of Naphthol, horses, 3J SS - * 3J V - '> dogs, grs. v. to 

 grs. xv. Sometimes conjoined with bismuth salicylate and 

 given suspended in mucilage. 



HYDRONAPHTHOL is a useful antiseptic and germicide, 

 soluble in one hundred parts of water and twenty of oil, 

 and often conveniently applied as a dry dressing, mixed with 

 twenty to thirty parts of fuller's-earth. 



NAPHTHALOL (Betol), prepared from /3-naphthol-sodium, 

 phosphorus oxy chloride, and sodium salicylate ; and alphol, 

 the salicylic ester of a-naphthol, are sometimes em- 

 ployed as intestinal antiseptics. In the bowel betol and 

 alphol are decomposed into salicylic acid and naphthol. 

 Benzo-naphthol, the benzoate of /3 naphthol, has been recom- 

 mended as a gastro-intestinal disinfectant. It is split up 

 into naphthol and benzoic acid (Coblentz). Benzo-naphthol 

 is very slightly toxic. Horses take grs. xxx. to grs. Ix. ; 

 dogs, grs. iv. to grs. viii., in bolus, pill, or electuary. 



PHENACETIN (para-acetphenetidine is produced by the 

 action of glacial acetic acid on para-phenetidine, a body 

 obtained from para-nitro-phenol (B.P.). It is white, taste- 

 less, odourless, occurs in glistening, scaly crystals, sparingly 

 .soluble in cold water, soluble in twenty parts of alcohol, 

 and in chloroform and glycerin ; insoluble in acid or 

 alkaline solutions. Like antifebrin and antipyrine, it 

 lowers temperature, diminishes pain, and depresses the heart. 

 Although its action is less rapid, it is more prolonged, 

 and less liable than either of these analogues to produce 

 collapse, while in human patients it has also slight soporific 

 effects (Brunton). Frohner and other German observers 

 state that grs. iii. to grs. vii. given to dogs in a febrile con- 

 dition lower the temperature 2 Fahr., also slow the pulse, 

 and relieve respiratory difficulty. These effects continue 

 for four hours. Horses and cattle take 3ij- to 3i v - 5 dogs, 

 grs. iii. to grs. xv., in bolus or electuary ; repeated at 

 intervals of two or three hours. 



PlPERAZlN (C 4 H 10 N 2 ), an organic base, produced by the 

 interaction of sodium glycol and ethylene-diamine hydro- 



