496 BELLADONNA AND ATROPINE 



alcohol (90 per cent.). An ounce is the dose for the larger 

 animals, TT[v. to TT[x. for the smaller. The tincture is given 

 in similar doses. 



The linimentum belladonna, prepared with liquid 

 extract 10, rectified spirit 7, camphor 1, and water 2, con- 

 tains 0*37 per cent, of alkaloids. Veterinarians frequently 

 extemporise an ointment by melting over a water bath 

 one part of extract and four of vaseline, and adding, as 

 the mixture cools, half a part of camphor. 



For external application, equal parts of belladonna extract 

 and glycerin may be used. It mixes readily with water. 

 The plaster is made by evaporating four ounces of the liquid 

 extract until it is reduced in weight to one ounce, and 

 adding five ounces of resin plaster previously melted 

 (B.P.). 



Atropine, being sparingly soluble in water, the sulphate 

 is generally used, and is about fifty times the strength of 

 the green extract. Subcutaneously the dose of atropine sul- 

 phate (one in twenty) for horses and cattle is gr. J to gr. 1J; 

 dogs, gr. ^L to gr. J (Trasbot). The B.P. liquor atropinae 

 sulphatis in general use, consists of grs. 17J of atropine 

 sulphate, grs. 2 of salicylic acid, and iv. of distilled water, 

 and contains one grain of the salt in 110 minims. For 

 horses and cattle the dose is f3i- to f3ij- J f r dogs, Tt|i. to 

 H\v. When used hypodermically, the minimum or still 

 smaller doses should be prescribed. Injeetio atropinse 

 hypodermica contains grs. jv. of atropine sulphate in j. 

 of water. Specially prompt and marked antispasmodic and 

 anodyne effects are secured, as stated, by conjoining about 

 equal proportions of atropine and morphine solutions. 

 For ophthalmic and other purposes, tissue papers containing 

 -g-Jrp and lamellae containing -j^y and -^-^ grain atropine 

 sulphate are convenient. The ointment is composed of 

 atropine, grs. 10, oleic acid, grs. 40, and lard, grs. 450. 



Homatropine hydrobromide, as already indicated, is 

 sometimes substituted for atropine sulphate for internal 

 administration, and still more frequently for eye cases. 

 To dilate the pupil, a solution, containing grs. iv. homa- 

 tropine hydrobromide, to the ounce of water or castor oil, 

 may be employed. 



