ACTIONS AND USES 501 



Several animals receiving three drachms of cannabis 

 extract, and others six drachms, manifested very similar 

 symptoms. The dulness and sleepiness, however, came on 

 more quickly, and were more marked, than when smaller 

 doses had been given. When moved, the subjects showed 

 unsteadiness on the fore-limbs, staggering, inability to trot 

 straight, the penis protruding. The faeces were discharged 

 at unduly long intervals, and in reduced amount. The 

 effects continued from twenty to twenty-six hours. Eight 

 drachms in bolus with linseed meal were given to a nervous, 

 kicking five-year-old. For two hours he tossed his head 

 incessantly, subsequently stood very quiet, but when touched 

 became excited, ate grass slowly, but left portions between 

 the lips. By the seventh hour he became very sleepy, took 

 no notice of any one, he was unsteady on his forelegs, the 

 body swayed backwards and forwards, the muscles about the 

 elbow and flank quivered, the penis was drawn about nine 

 inches. There was no movement of the bowels for sixteen 

 hours. By the twenty-fifth hour he brightened up ; and 

 in thirty hours was again normal. A second horse received 

 eight drachms cannabis extract ; in three and a half hours 

 he became sleepy, with penis drawn three to four inches. 

 An hour later the head was down, the eyelids almost closed, 

 the lower lip pendulous. He was unsteady on his legs, 

 swayed backwards and forwards, took no notice of flies 

 on face or body, when trotted, did so sideways and very 

 unsteadily, the pulse and respiration were lowered. For six 

 hours he remained in the same quiescent sleepy state, notic- 

 ing nothing, and did not lie down during the night. By the 

 twenty-fourth hour he got brighter, but was still unsteady 

 on his limbs. No dung was passed for thirty hours, when 

 some dry, small pellets were discharged. Although continu- 

 ing quiet, he gradually became lively, and in thirty-five 

 hours was perfectly recovered. Hobday states that doses of 

 ten grains to two drachms of extract, administered to dogs, 

 although quickly causing stupor, with paralysis of the 

 hind-limbs which might continue one or two days had 

 never proved fatal, these effects gradually passed off, and 

 their removal was expedited by cocaine. 



Indian hemp has proved serviceable in abating the 



