SAVIN 625 



of the drug are quite inactive. Proper physiological 

 standardisation is necessary, and without this there is no 

 certainty of action. 



DOSES, etc. Ergot freshly powdered, as an ecbolic for the 

 mare or cow, 5 SS - to %ij. ; for sheep about 39 '> f r swine 

 and bitches 3s. to 3J- ; Extract of Ergot (Ergotin), horses 

 and cattle, grs. xxx. to grs. Ixxx. ; dogs, grs. v. to grs. x. ; 

 in drench or electuary, and repeated as may be required. 

 The liquid extract may be prescribed for horses and cattle in 

 doses of H\lx. to 39- 5 f r dogs, H\x. to Tl\xxx. Of the 

 tincture horses and cattle may be given "^iv. to j. or more. 

 The B.P. hypodermic injection of ergot contains 33 grains 

 of the extract in 110 minims. For the mare or cow the dose 

 is 1T[60 to H\100 injected subcutaneously or into the substance 

 of the gluteal muscles. The smaller dose should first be 

 tried. 



SAVIN 



SABINA CACUMINA. Fresh and dried tops of Juniperus 

 sabina, collected in spring from plants cultivated in 

 Britain. Nat. Ord. Coniferse. (U.S.P.) Not official 

 in B.P. 



Juniperus sabina is an evergreen shrub, common through- 

 out Middle and Southern Europe, and cultivated in this 

 country. The tops of young branches, with their attached 

 leaves, when fresh are green, but become yellow when kept ; 

 have a strong, heavy, disagreeable odour, and a bitter, acrid, 

 resinous taste. They communicate their properties to 

 water, spirit, and the fixed oils, and owe their activity to 

 about three per cent, of a colourless or pale yellow volatile 

 Oil, prepared from the fresh tops by distillation, isomeric 

 with oil of turpentine (C 10 H 16 ), and associated, as constantly 

 occurs in plants, with a more oxidised oil (C 10 H 16 0). From 

 the berries ten per cent, of these oils is said to be obtained 

 (Phillips). 



ACTIONS AND USES. Savin is a topical irritant, antiseptic, 

 rubefacient and vesicant. Administered internally, moder- 

 ate doses are anthelmintic and diuretic ; they increase 

 appetite, promote digestion, and stimulate the urino-genital 



2E 



