240 BACILLI OF THE HEMORRHAGIC SEPTICEMIA GROUP 



40. What animals are susceptible to the pathogenic action of the bacillus; 

 how does natural infection occur? 



41. Discuss the canine disease known as dog typhus or gastro -enteritis hemor- 

 rhagica. 



42. What organism causes bubonic plague in man, rats, and other animals? 



43. Define and describe a plague bubo. 



44. Define the following terms: primary bubo of the second order; secondary 

 bubo of the first order. 



45. What lymph glands in rats are most commonly the seat of the primary 

 bubo? 



46. Name the lymph glands affected in the order of their frequency. 



47. Describe the liver changes frequently found in rats dead from plague 

 infection. 



48. Describe the appearance of the subcutaneous connective tissue after 

 removal of the skin. 



49. What pathologic change in the pleura is very typical for rat plague? 



50. What other animals in general are said to be susceptible to natural plague 

 infection? What other rodents in addition to the rat are susceptible? 



51. How is plague infection spread from rat to rat and from rat to man? 



52. Is the general transmission by rat fleas proved beyond doubt? If not, 

 why not? 



53. Discuss the finding of plague bacilli in plague -sick rats. 



54. Is plague in man generally a true septicemia? 



55. What is latent plague? Among what animals or human beings does it 

 occur? 



56. Describe the morphology and staining properties of the Bacillus pestis. 



57. Describe its cultural properties. 



58. Discuss its resistance. 



59. Have vaccine and serumtherapy been tried in plague, and how? 



