CULTURAL PROPERTIES 



429 



growth is comparatively compact and difficult to remove with the 

 platinum loop. On gelatin, after several weeks, a yellowish, sand-like 

 mass is formed, liquefaction of the medium does not occur. On 

 potatoes the growth appears more rapidly, and is of a dirty white, 

 smooth, lusterless character. In bouillon, whitish flocculi, which 

 slowly sink to the bottom, are formed. Inoculation of pure cultures 

 into horses and small laboratory animals is rarely if ever followed by 

 the production of typical lesions, 



but pus containing the organ- FlG - 175 



isms when inoculated into 

 equines has produced the pic- 

 ture of the disease. Tokishige 

 was able to infect horses and 

 to produce abscesses and nod- 

 ules. None of the experi- 

 mental inoculations brought 

 about a progressive fatal case. 

 Strong produced nodules in 

 monkeys inoculated with pus 



FIG. 174 



Photomicrograph of pus from a lymph 

 nodule in a horse suffering from blastomy- 

 cosis, showing intra- and extra-cellular blas- 

 tomyces. (Strong.) 



Blastomycotic lymphangitis in a North 

 Dakota mare. (Mohler. 1 ) 



from naturally infected horses. As the organism in artificial cultures 

 does not ferment any of the sugars, the names Saccharomyces farcimi- 

 nosus and Lymphangitis saccharomycotica are misnomers and should 

 be replaced by Blastomyces farciminosus and Lymphangitis blasto- 

 mycotica. The organism in artificial cultures forms mycelia-like 

 filaments composed of oblong or cylindrical cells. 



