QUESTIONS 433 



BLASTOMYCES THE CAUSE OF TUMORS? 



A number of investigators, particularly Sanfelice, have claimed 

 that blastomyces are the cause of malignant tumors in man and the 

 lower animals, but these claims have not been confirmed. Sanfelice 

 reported the finding of a pathogenic blastomyces in a cancer of the 

 liver in an ox, and since the pathologic lesion was calcified he named 

 the organism Saccharomyces lithogenes (lithogenes, stone-forming). 

 Another organism obtained from nodules in the lung of a hog was 

 described by the same author as Saccharomyces granulomatogenes. 1 



QUESTIONS. 



1. What is the common English name for Saccharomyces? 



2. What is the meaning of the term blastomyces? 



3. Describe the process of budding. 



4. Why have saccharomycetes been classified as ascomycetes? 



5. Define the terms: ASCIIS, endogenous ascospares. 



6. What is the difference between a typical Saccharomyces and a torula? 



7. Do saccharomycetes, by budding, always form new individual unicellular 

 globular organisms? If not, what do they form? 



8. Describe the finer details of the structure of a blastomyces. 



9. How can blastomyces be stained in cover-glass preparations? How in 

 tissue sections? 



10. What is pseudofarcy in horses? 



11. Describe its pathologic lesions. 



12. Name and describe its cause. 



13. Describe the cultural properties of the Blastomyces farciminosus. 



14. Have any other blastomyces been found in pathologic lesions in horses? 



15. What is blastomycetic dermatitis in man? 



16. Describe its pathologic lesions. 



17. Describe the organism causing it. 



18. What is Saccharomyces lithogenes and Saccharomyces granulomatogenes? 



1 A complete list of budding fungi occasionally found in pathologic lesions is given in Busse'a 

 contribution on "Sprosspilze" in Kolle and Wassermann's Manual, vol. i, p. 661. 



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