744 



Mycetoma, or Madura-foot 



round cells. The youngest nodules consist of granulation-tissue, 

 whose development is checked by early coagulation-necrosis. Giant- 

 cells are few. 



Not infrequently small hemorrhages occur from the ulcers and 

 sinuses of the diseased tissues; the hemorrhages can be explained by 

 the abundance of small blood-vessels in the diseased tissue. 



Fig. 307. Melanoid form of mycetoma. Section showing black granules 

 and general features of the lesions as they appear under a low-magnifying power. 

 Zeiss at (James H. Wright). 



Fig. 308. Melanoid form of mycetoma, showing structure and appearance 

 of the hyphae of the mycelium obtained from the granules. Zeiss apochromat; 

 4 mm. (James H. Wright). 



The Melanoid Form of mycetoma has been carefully investigated 

 by Wright* and appears to depend upon an entirely different micro- 

 organism properly classed among the hyphomycetes. It is probably 

 identical with the organism described by Boyce and Surveyor. 



In the case studied, Wright found the diseased tissues, consisting 



* "Journal of Experimental Medicine," 1898, vol. m, p. 421. 



