20 ACTION OF ANTHELMINTICS ON PARASITES. 



Borini cite no post-mortem findings or final negative fecal examina- 

 tions in support of their statements. Among the cases reported by 

 Railliet, Moussu, and Henry, autopsy showed that Fasciola hepatica 

 in four cases and Dicroccelium lanceatum, in all cases had survived 

 the full dose advocated by them. None of Joannides's cases were 

 followed by post-mortem examination; and, so far as case records 

 are available, no cases of bilharziasis treated by male fern have been 

 followed by post-mortem examination to ascertain whether the ad- 

 ministration of the male fern had resulted in the death of the flukes. 

 In spite of these objections, the total evidence collected here indi- 

 cates that further work along this line is necessary and desirable. 

 It is possible that the common opinion that medicines administered 

 per orem or subcutaneously can not be successfully used against 

 metazoan parasites outside of the digestive tract, that the higher 

 orders of parasites can not be killed by a selective action of drugs 

 without injury to the host animal in whose tissues they are located, 

 may be erroneous. Improved technic and better medicines have 

 marked great advance in the treatment of protozoan and bacterial 

 diseases. Similar improvements have led to greater success in the 

 treatment of intestinal helminthiasis. May not careful experiment 

 lead to the same results in the treatment of somatic and extra- 

 intestinal helminthiasis? The subject is worth investigating. The 

 location of metazoan parasites often makes surgical treatment im- 

 possible, dangerous, or unprofitable. Adequate methods of medici- 

 nal treatment w r ould have great medical and economic value as well 

 as scientific interest. The present state of our knowledge does not 

 warrant any conclusion other than this, that a great amount of addi- 

 tional work is necessary and desirable. 



BIBLIOGRAPHY. 1 

 ALESSANDRINI, GIULIO. 



1908. Contribute allo studio delle malattie parassitarie delle pecore <Boll. 

 Soc. zool. ital., Roma, v. 17, 2. s., v. 9 (11-12), pp. 392-400, 1 table. [W*.] 



BOBINI, AGOSTINO. 



1911. La distomatosi e sua cura <Gazz. d. osp., Milano, v. 32 (143), 28 

 nov., pp. 1515-1516. [W m .] 



CONOR, A. 



1911. Bilharziose et 606 <Bull. Soc. de path, exot, Par., v. 4 (1), 11 Jan., 

 pp. 45-47. [W*.] 



CUBTICE, COOPER. 



1889a. Tapeworm disease of sheep of the western plains <4th & 5th Ann. 



Rep. Bureau Animal Indust, U. S. Dept. Agric., Wash. (1887-88), pp. 



167-186, pis. 1-2, figs. 1-15. [W a .] 

 1890c. The animal parasites of sheep. 222 pp., 36 pis. 8. (U. S. Dept. 



Agric.) Washington. [W".] 



lf This bibliography is prepared in the style used in Bulletin 39 of this bureau, Index- 

 Catalogue of Medical and Veterinary Zoology. 



