AUTHOES EXPERIMENTS. 17 



appearances similar to those of hemorrhagic septicemia. Death was perhaps 

 hastened by the administration of carbon bisulphid. No Thysanosorna or lesions 

 attributable to this worm were found. 



4. Administered 6 grams of carbon bisulphid in capsule. Fifty hours later 

 administered 4.5 grams of carbon bisulphid and repeated this dose 24 hours 

 later. Killed the sheep 20 hours afterwards. No tapeworms were found on 

 autopsy, but the gall ducts were thickened and enlarged, as was also the 

 pancreatic duct, probably the result of former infestation with Tliysanosoma. 

 No worms had been found, however, in the feces of this or any of the other 

 sheep. 



5. Administered 6 grams of carbon bisulphid in capsule. Fifty hours later 

 administered 3.5 grams of carbon bisulphid and repeated this dose 24 hours 

 later. Killed the sheep 20 hours afterwards. No tapeworms were found on 

 autopsy. 



6. Administered 6 grams of carbon bisulphid in capsule. Forty-eight hours 

 later sheep was down, with a respiration rate of 210. Sheep found dead 24 

 hours later. No evidences of the efficacy of the drug that is, dead specimens 

 of TJiysanosoma were found. Other notes regarding this autopsy lost. 



A summary of the above experiments shows that sheep No. 1 had 

 live tapeworms in the liver and intestines after receiving two doses 

 of 6 grams each of carbon bisulphid on two successive days; that 

 Nos. 2 and 3 after the same treatment had no tapeworms or lesions 

 indicating their presence ; and that Nos. 4, 5, and 6 showed no dead 

 tapeworms on autopsy. As stated before, no tapeworms were found 

 in the feces of any of these sheep. These experiments were incon- 

 clusive, but they point to the inefficacy of carbon bisulphid in that 

 where tapeworms were found, as they were in one case, after 12 

 grams of carbon bisulphid had been administered, the tapeworms 

 were alive. 



It should be noted in this connection, as a matter of passing inter- 

 est, that no stomach worms were found in these sheep on post-mortem. 



The next set of experiments was made by both of us at Mr. Wells's 

 ranch later in July. This time four sheep, selected as probably suffer- 

 ing from Thysanosoma infection, were used to test the ethereal extract 

 of male fern, and two sheep in good condition were used to test the 

 proprietary medicine previously referred to. The experiments were 

 as follows: 



Sheep Nos. 1 and 2 were given two tablets each of the proprietary 

 medicine, according to the directions furnished with the medicine. 

 No. 1 was killed 24 hours later. A number of Thysanosoma were 

 found in the gall bladder and intestine, and flwmonchits contortns 

 and Ostertagia bullosa in the fourth stomach. All the worms were 

 alive, although the advertisement of the remedy claimed that the 

 dose given would kill any worm in the digestive tract. No. 2 was 

 killed 48 hours after receiving the dose. Specimens of Thysanosoma 

 were found in the gall ducts, two in the pancreatic duct, and a num- 



