33 



ovum; and it is not in')robabl*^ that they are, in nart at 

 least, the result of nuclear activity. During the formation 

 of these bodies, the nucleolus shows signs of being in an 

 active condition and ^ay also be connected with their manu- 



A 



facture. In sorr.e stages the -'urleolus is der.se a-d horno- 

 geneous; in others iz has one or tv;o clearer globules in 

 its interior. These facts see-i to show that it is not in a 

 dormant state; and it is DXossibe that it -ay be associated 

 in some way with the transformation of the absorbe ; nroto- 

 nlasT into deut^cnlas"^ At least that the yoll: spheres arise 

 directly through the activity of the cytonlasr;, indepen- 

 dently of any nuclear or nucleolar function, is doubtful. 

 £er If aa^ were the case we wou.ld exnect the yolk bodies to 

 arise in other parts of the cvu~ than around the germinal 

 vesicle. Thai this orcurs there is no evidence from the studj 

 of rrany eggs, The primitive ovarian cells are all, or nearly 

 all, absorbed and used in the ranufacturo of the yolk gran- 

 ules by the growing ova, except a layer at the outside v;hich 

 is transforTed into the emithelium of the ovary. The cells 



