counts the percentage, of ingesting leucocytes as well as the 

 total number of intx'acellular bacteria were determined. 



Fig. 2, taken from the Johns Hopkins Hospital Bulletin (18) 

 illustrates the appearance of the cells from which the enumera- 

 tions recorded in this paper were made. 



SUBJECT MATTER 

 The data presented in this paper are selected from, a 

 study of 85 cases of infection and intoxication which resulted 

 in death. An effort was made to secure the widest possible 

 variety, including both spontaneous and induced infections in 

 animals, supplemented by a series of human cases. The period 

 elapsing between the primary inoculation and death ranged from 

 a few hours to several weeks, and even much longer in some of 

 the human cases. The arrangement of subject matter and condi- 

 tion of each experiment are clearly set forth in the various 

 protocols . 



EXPERIMENTAL DATA 

 PART 1 

 A. Pneumococcus Infections 

 Experiment 1. — The dog - No. 11 - used in this experi- 

 ment was an adult female weighing 15^ pounds. It was inoculated 

 intravenously on November 27, 1920, with a sublethal dose of 

 virulent Pneumococcus, Type I. The sublethal doses were con- 

 tinued on dates indicated in the protocol until the blood ex- 

 hibited a high bacteriotropic action. The intravenous inocu- 



(9) 



