Anatomical Dia^'^nosis: 



Slight emaciation, bronchopneumonia, 

 purulent exudate in both pleural cavities, 

 generalized edema. Pneumococcus , '-^ype I, 

 cultivated in pure culture from pleural 

 exudate and from heart blood. 



Kataphylaxis is this animal probably occurred on Jan- 

 uary 20, five days before its death, and was first indicated 

 by the appearance of pneumococci in the blood sufficient quan- 

 tity to be recovered in the culture. By referring to the 

 curves in Fig. 3 it will be observed that there was no post- 

 kataphy lactic decline in the opsonic index for any except the 

 specific infecting organism. Samples of blood taken a few 

 moments before death, when the animal was in a state of com- 

 plete collapse, revealed a phagocytic activity in all respects 

 equal to the normal and for staphj'-lococci it was even somev.hat 

 increased. 



The opsonic index for the infecting or^^anism behaved 

 throughout in accordance with the findings published by Keu- 

 feld and TBpfeT (19) and Rosenow (20). Virulent pneumococci 



(13) 



