Anatomical Diagnosis: 



r.iarked emaciation, purulent exudate in 

 pleural cavities; kidneys studded with small 

 abscesses. Pelvis of each kidney and bladder 

 contained pus. Staph, aureus in pure culture 

 cultivated from pleural cavities, kidneys, 

 bladder and heart's blood. 



This case represents an infection of the most violent 

 and destructive character. The animal lost 28/j of its body 

 weight in five days. The pleural cavities and urinary system 

 were filled with pus containinf^ abundant organisms, and the 

 staphylococci were so numerous in the blood stream at death 

 that 2000 colonies were cultivated from a single loop-full of 

 blood. Yet in spite of this tremendously overwhelming infec- 

 tion the phagocytic system suffered practically no impairment. 

 Only the opsonic index for the specific organism was below the 

 normal, and this by a difference so small that it mijht easily 

 be regarded as an experimental error. That the test affords 

 an accurate estimate of conditions in the body is attested by 

 the fact tnat many of the polymorphonuclear leucocytes of the 

 blood were activeljr phagocytic, some containing as many as 

 35 cocci. Likewise, almost every polymorphonuclear leucocyte 

 examined from the pleural exudate contained organisms. This 



(24) 



