case is perhaps somewhat exceptional, especially the phagocy- 

 tosis in the exudates, for Opie (25) has shown that exudates are 

 often deficient in opsonins. It does, however, indicate that 

 phagocytic collapse does not always accompany fatal infection. 



Experiment 7. — The guinea pig -No. 17 - selected for 

 this experiment weighed 360 grams. It was injected intraven- 

 ously with 2 CO. of a 24 hour broth culture of Staph, aureus . 

 Death occurred at the end of eighteen hours. 



The experimental details are sumrnerized in the follow- 

 ing table. 



Anatomical Diagnosis: 



Ko macroscopic lesions. Heart blood 

 yielded a pure culture of Staph, aureus . 



A review of the preceeding staphylococcus infections 

 reveals that^ overwhelming of an animal by Staph, a ureus may b( 

 accompanied by a sharp and subnormal decline in the opsonic 

 index for that organism, but that this is not invariabljr the 

 condition. It would seem that especially in rapidly fatal 



(25) 



