infections the phagocytic activity may not be disturbed. 



In these cases, no matter how violent and destructive 

 the cause of the infection, no matter how exhausted and wasted 

 the animal, there V;as not one instance of a decrease in phago- 

 cytic activity, even in the hours immediately preceeding death, 

 against any organism not concerned in the primary infection. 



C. Typhoid Infections 



Experiment 8. — In this experiment an adult male dog - 

 No. 13 - weighing 13-^ pounds was injected intravenously on 

 November 27, 1920, vsith 2 cc. of an IS hour broth culture of 

 B. typhosus . Sublethal inoculations v;ere continued until the 

 blood revealed a high opsonic content and then the injections 

 were gradually increased until the dog died on December 2S , 

 1920. 



Samples of blood were taken before each injection and 

 the usual opsonic determinations made under the conditions de- 

 scribed in the followinn- table. 



(26) 



