cific organism was below normal at the time of death. The 

 opsonic indices for the heter;logous bacteria, in each instance, 

 differed from the normal by less than v;hat can properly be 

 regarded as experimental error. 



There was in the study of cat No. 37 one feature of 

 very special significance and interest. Tnis animal when first 

 examined on February 15th already revealed advanced emaciation 

 and weakness. The blood culture on this date showed an abund- 

 ance of streptococci and a few colonies of Staph, aureus . Two 

 days later this latter organism waB found abundantly in the 

 blood, but by February 19th it had considerably decreased and 

 had completely disappeared before the cf.t died on February 20th. 

 Ten cubic centimeters of blood cultured at the time of autopsy 

 failed to develop a single colony of Staphylococci. Strepto- 

 cocci were sufficiently numerous in the blood at all times to 

 be recovered hy plating a single loop of blood. 



Vvhen this cat was placed under observation it was the 

 subject of a double infection and showed evident indications 

 of being rapidly overcome. That the streptococcus was the 

 dominant etiological factor' in the infection seems evident from 

 the fact that the symptoms revealed by this cat were in every 

 way similar to those in animals suffering with a pure strept- 

 coccus infection. 



Cat No. 37, then, was being overcome by a rapidly fatal 

 infection. It had in some way become secondarily infected with 

 Staph, aureus, and this latter organism had become so abundant 



(38) 



