exact agreement throughout with the results previously obtained 

 endows these findings with considerable significance. 



The method of procedure was the same as that emploj'-ed in 

 previous experiments. A sample of blood was obtained from the 

 patient, or if from autopsy, as soon after death as possible, 

 and after two hours the serum was separated and the usual op- 

 sonic determinations made. The control serum and leucocytes 

 were obtained from a normal individual at the same time the 

 experimental sample was taken. In some instances leucocytes 

 were also obtained from the patient and here the "cytophagic" 

 as well as ihe opsonic index v/as determined. These results 

 are given in a subsequent table. 



The experimental conditions and results of the study of 

 human cases are tabulated below. 



Case No. 1. 



Clinical History: 



'.'.'hite female; age 69 years 



Duration of present illness: July 1920 until 

 March 8, 1921. 



Entered hospital January 22, 1921; died March 8, 1921. 



Diagnosis: Arteriosclerosis, hypertension, chronic 

 nephritis, hemiplegia, acute bronchopneumonia.. 



Bacteriology: Blood culture repeatedly negative. 



*The clinical and autopsy data of the following human 

 cases were secured from the Johns Hopkins Hospital records. 



(46) 



