GONGLUSIONS 



The results obtained in this investigation would seem 

 to warrant the following conclusions: 



1 . Although thsre is sometimes a decrease in the onaonic 

 in.iex for the specific infecting organism during the 1-ite stages 

 of fatal infections, there is no decrea.-.e in the phagocytic activ- 

 ity against any bacteria not concerned in the primary infection. 



2. Neutrophilic leucocytes from an animal in the late stages 

 of a fatal infection are as actively phagocytic as normal cells 

 when placed in a medium containing suitable opsonins. This in- 

 dicates that there is no decrease in the phagocytic function 



of these cells. 



3. The "differential" opsonic index is a more reliable 

 measure of the animal's phagocytic capacity than the '7right 

 opsonic index. 



4. Absolute depression in phagocytic effectiveness 

 against the infecting organism is not an Invariable phenomenon 

 in fatal infections. 



In closing this paper I v/ish to thank Dr. MacCallum for 

 his courtesy and assistance, and I desire to -icknowledge a very 

 especial debt of gratitude to Dr. Bayne- Jones for the substan- 

 tial contributions he has made to the development of this problem. 



(63) 



