TREATMENT WITH NEW TUBERCULIN 69 



cause for the non-employment of tuberculin. Only where absolute ca- 

 chexia, without any possibility for improvement exists, is this therapy to be 

 omitted. In all other conditions, an attempt is by all means justified. 

 Experience, of course, plays an important r61e in the selection of suitable 

 cases. For a beginner, it is advisable to gain practice by the treatment of 

 uncomplicated cases before undertaking those of greater difficulty. 



2. New Tuberculin-Bacilli-Emulsion (B. E.) and New Tuberculin T. R. 



Treatment with new tuberculin follows along the very same lines set 

 down for old tuberculin. 



New tuberculin T. R. is the mildest of all preparations. It is very 

 suitable for the beginning treatment of susceptible patients. When the in- 

 dividual does not react to large doses, it is well to start in with B. E. 

 B. E. can also be employed without producing any reaction, although it 

 is somewhat more difficult. 



The dosage scheme advised by Bandelier and Rcepke is as follows: 



i/iooo, 2/1000, 3/1000, 7/1000, 10/1000 mg., 

 15/1000, 2/100, 3/100, 5/100, 7/100, 10/100 mg., 



At intervals of i to 2 days; 

 15/100, 2/10, 3/10, 5/10, 7/10, 10/10 mg., 



At intervals of 2 to 3 days; 

 12/10, 15/10, 2, 2 1/2, 3, mg., 

 At intervals of 3 to 4 days; 



4, 5> 6, 7, 8, 9, 10 mg., 

 at 4 to 6 to 10 days intervals. 



In susceptible patients, it is best to increase the dosage only by one- 

 half mg. even when large doses are administered. Ten mg. B. E. represents 

 the maximum dose. 



The author himself follows a different scheme from that of Bandelier 

 and Rcepke. The injections are given less frequently, only about once a 

 week, but the dose is always increased twofold, fivefold and even tenfold 

 without any excessive reactions. 



Fever is obtained much less often with new tuberculin than with T. 

 The reaction usually is in the form of lassitude, nausea, weakness, in- 

 somnia, etc. 



The treatment with new tuberculin is particularly favorable in cases 

 where a low continuous fever is present. It also is more potent in destroy- 

 ing the bacilli of the sputum. The author therefore prefers the B. E. to 

 all other tuberculin preparations. Bandelier and Rcepke have also ob- 

 tained gratifying results with the B. E. therapy as is evident from the 

 following statistics of 205 patients treated at the sanatorium at 

 Kottbus. 



