ALTERATION OF CELLULAR ELEMENTS OF MATRIX. 75 



presented itself here with the greatest distinctness on those spots 

 where the endothelium had become detached. Here one had to do 

 with a centrum tendineum quasi-pencilled. 



In many places the system of lymph-canaliculi of the peritoneal 

 serosa contained migratory cells ; on other places the branched cells 

 were also very distinct, besides that the outlines of the lymph-cana- 

 licular system were recognisable. 



On places such as these one could perceive a striking difference 

 in the individual parts of the lymph-canalicular system in reference 

 to that of other places. First, it was clear that the lacunae were 

 larger, the canals were not branched and not so abundant, and 

 secondly, they appeared wider at many places. When one directed 

 one's attention to one of the widest of the canals, one could discover 

 on them one or even several small dilatations. As for the branched 

 cells of the lymph-canalicular system, it is to be noticed that they 

 are distinctly recognisable by their granular appearance, and by the 

 presence of their nucleus. In many of them it was possible to trace 

 the protoplasm of the cell body, which lay in the lacuna, into the 

 canals ; in the wide canals which, as above described, were furnished 

 with lacunae-form bulgings, a swelling corresponding to this bulging 

 could also be demonstrated on the protoplasm or on the protoplasmic 

 processes. As for the nuclei, constrictions could be remarked upon 

 them, and some of the cells were furnished with two nuclei. 



From this appearance one is able without doubt to draw the 

 conclusion that both the lymph-canalicular system and also its 

 contents, viz. the branched cells, have undergone changes : the 

 lacunae and canals, or the cell body and cell processes respectively, 

 were swollen, the canals or cell processes reduced in number, less 

 branched, and finally, the nuclei of the cells in the act of division. 

 4n nhiVction r-..-inst these deductions can be made all the less as we 

 LO do h ha change of the lymph-canalicular system and 



of the cells whi_ ot be attributed to any cause of the method 



of preparation. i we pass from the places just described to 

 places where the endothelium of the surface is also remove^, and 

 where consequently colouration of the matrix has occurre^ but 

 where the lymph canalicular m contains migratory cells, the 



