URINE. 235 



urine, that the quantities of fixed salts, and also of extractive 

 matters, are likewise less than in the normal secretion ; that, on 

 the other hand, the morbid urine contains albumen, which is 

 altogether absent in a state of health. 



My own analyses give a similar result, at least as far as the 

 urea is concerned. I have recently analysed the urine of a young 

 man 21 years of age, suffering from Bright 5 s disease, which was 

 remarkable for the large quantity of albumen it contained. He 

 had been attacked with anasarca and ascites, and the urinary 

 secretion was diminished to about 12 ounces in twenty-four 

 hours : the urine was of a dark-yellow colour, had an acid reac- 

 tion, and formed a whitish mucous sediment, which, when 

 examined under the microscope, appeared to consist, at least 

 for the most part, of long, articulated tubes, similar to those of 

 the conferva, which were in part filled with a dark granular 

 matter; there were, moreover, many globules filled with the same 

 matter, which resembled Gluge's inflammatory globule; there 

 were also mucus- or pus-granules, and in one instance a slight 

 quantity of very beautifully-crystallized yellow uric acid. I have 

 since examined the sediment in various cases of this disease, 

 and find that this appearance is by no means uncommon. To 

 the naked eye sediments of this nature resemble a little mucus, 

 but on carefully pouring off the urine and examining the deposit 

 under the microscope we observe : 



1st. Mucus-corpuscles of the ordinary size, more or less 

 granular, and decidedly nucleated. Fig. 31, a. a. 



2dly. Pavement epithelium, from the mucous membrane of 

 the bladder. Fig. 31, b. b. 



3dly. Blood-corpuscles. Fig. 31, c. c. 



4thly. Round dark vesicles apparently filled with granular 

 matter, and varying in diameter from -0006 to -0009 of a French 

 inch. They strongly resemble Gluge's inflammatory globule. 

 Fig. 31, d. d. 



5thly. Tubes composed of an amorphous matter, resembling 

 coagulated albumen. Fig. 31, e. e. That these tubes have in 

 most cases an actual capsule and are cylindrical may be seen 

 by inclining the stage, when they will rotate in the fluid in 

 which they are floating. In some the capsule appears to be 

 absent, and we can then see an amorphous, finely granular 

 mass, adhering in a cylindrical form. Some of these tubes are 



