URINE. 257 



and would be darker, more acid, and of higher specific gravity 

 (1021-8) in the hot stage. 



Becquerel occasionally observed sediments in the urine at 

 the termination of the paroxysm, but they were by no means 

 of constant occurrence : Andral observed the same. He only 

 noticed them in those cases in which the fever was intense and 

 prolonged, and terminated in a very abundant perspiration, or 

 when it was complicated with functional derangements, or with 

 congestion of certain organs. 



The sediment formed in intermittent fevers is always com- 

 posed of uric acid and urate of ammonia, in most cases combined 

 with red colouring matter (uroerythrin) . 



A very perfect crisis by the skin and kidneys is said to indi- 

 cate an erethismic type of fever ; an imperfect and slight one, 

 occurring through only one of the secreting organs, a synochal 

 type ; and a colliquative crisis, a fever of a torpid character. 



In a young man aged 23 years, who was treated in our hos- 

 pital for quartan fever, the urine, at the end of the paroxysm, 

 always threw down a copious, yellowish-red sediment. During 

 the intermission it was secreted more copiously, was clear, of 

 an amber-yellow colour, contained a few mucous flocculi, and 

 had a slight acid reaction. 



[The following table, drawn up by L'Heretier, 1 represents 

 the mean composition of the urine in the different stages of 

 this disease, as deduced from the analyses of the urinary secre- 

 tion of twelve patients : 



Cold stage. Hot stage. Sweating stage. 



Specific gravity . -. 1017*330 1020-304 1022-820 



Water . . . 967-520 964-680 961-845 



Solid constituents . . 32-480 35-320 38-155 



Urea . . . 9-845 9-015 7-624 



Uric acid . . 0-660 0-980 1-029 



Salts and organic matter . 21-975 25-325 29-502 



In all these cases the physical characters of the secretion 

 were affected by the disease ; in six other cases the urine re- 

 mained apparently normal.] 



1 Traite de Chimie patholog. p. 528. 



ii. 17 



