URINE. 271 



Cholera. 



In sporadic cholera, as well as in the Asiatic form of the 

 disease, the urinary secretion is very scanty, and sometimes 

 altogether suppressed. Any urine that is discharged is usually 

 of a dark colour, and has a feeble acid reaction, but its specific 

 gravity is below the healthy average. 



In a case which I observed in our hospital, where the symptoms 

 were exhibited with great severity in a woman 36 years of age, 

 there were frequent evacuations by stool, but only about one 

 ounce and a half of dark acid urine, with a specific gravity of 

 1011-0, in the course of twenty -four hours. I only determined 

 the amount of solid constituents collectively, and of the urea. 



In 1000 parts I found : 



Analysis 118. 



Water .... 975-90 

 Solid constituents . . . 24-10 



Urea .... 7-10 



The urea in this case amounts to rather more than 29 of 

 the solid residue, which is considerably below the normal pro- 

 portion. At the approach of convalescence the urine was 

 discharged more copiously, but it continued to be deeply co- 

 loured : it was only after some days that it became pale and 

 anaemic. I never observed any sediment. 



[The urine of a man aged 30 years, attacked with sporadic 

 cholera, was analysed by Heller. 1 There was excessive diar- 

 rhoea and vomiting, and the patient died on the fourth day. 



During the first forty-eight hours of his illness only one ounce 

 of urine was discharged; it had a deep golden-yellow colour, 

 and deposited earthy phosphates although strongly acid. Its 

 specific gravity was 1018. It contained in 1000 parts : 



Water and free carbonic acid . . . 955-67 

 Solid constituents .... 44-33 

 Urea ..... 10-50 

 Uric acid ..... 0-10 

 Extractive matter, with a large quantity of a peculiar sub- 

 stance apparently originating from the bile . 27*32 

 Fixed salts ..... 6-41 J 



1 Archiv fiir phys. und pathol. Chemie, vol. 1, p. 15. 



