URINE. 



277 



The fixed salts contained no trace of chloride of sodium, 

 the normal amount of earthy phosphates, a slight excess of 

 alkaline phosphates, and an augmentation of the sulphates, 



Hippuric acid was sought for without success. 



Oxalate of lime is of frequent occurrence in cases of acute 

 rheumatism.] 



In chronic rheumatism, if the pains are not very acute, and 

 the night's rest is not disturbed, the urine retains its normal 

 properties. Out of thirty-seven cases observed by Becquerel, 

 the urine remained unaffected in twenty, while in seventeen it 

 assumed the inflammatory type, and in nine of these threw down 

 a spontaneous sediment. 



Gout. 



I have made four analyses of the urine in two cases of gout, 

 with the view of determining the effect of benzoic acid on that 

 secretion : 



If we determine the per centage of the urea and uric acid in 

 relation to the solid residue, we find in the first case, that be- 

 fore the use of benzoic acid the urea amounted to 3O16g and 

 the uric acid to 2'14, and afterwards they amounted to 28'21 

 and 2'22g respectively. In the second case the urea and uric 

 acid amounted to 26*56 and 1'66 before the use of the acid, 

 and 26-61 and 1'59 afterwards. 



These analyses are insufficient to show that benzoic acid exerts 

 any influence on the amount of urea or uric acid. The clinical 

 experiments of Froriep and others indicate, however, that it is 

 a valuable remedy in various forms of arthritis. 



Froriep 1 has published a notice of twenty cases of gout and 



1 Simon's Beitrage, p. 294. 



