294 THE SECRETIONS: 



and Henry, to be diminished, while they retain their normal 

 proportion to each other. I have found the amount of earthy 

 phosphates not much below the normal average. 



Lehmann 1 was the first who directed attention to the 

 occurrence of hippuric acid in diabetic urine : it has since 

 been detected by Ambrosiani, Miiller, and very recently by 

 myself. I obtained it in the same manner as Lehmann did, 

 from the etherial solution of the dried residue : after evapora- 

 tion there remained a slight brownish-yellow residue, in which, 

 with the help of the microscope, I observed heaps of long 

 acicular crystals. The residue was warmed with a few drops of 

 a weak solution of potash, which neutralized the acid reaction, 

 and the solution was then filtered. On the addition of a solu- 

 tion of perchloride of iron a cinnamon-yellow precipitate was 

 obtained, which on being warmed contracted itself into red 

 flocculi. 



On allowing diabetic urine to stand for a considerable time 

 a sediment forms which consists for the most part of fermenta- 

 tion-globules. If the urine above this sediment is allowed to 

 remain for some time longer at a suitable temperature, it begins 

 to undergo fermentation. I have frequently observed the fer- 

 mentation-globules, and have represented them in fig. 35. 



I have made several minute analyses of the urine in diabetes 

 mellitus. The three following analyses were made with the 

 urine of a man aged 50, to whose case reference has been pre- 

 viously made. The first analysis was made at a time when the 

 patient indulged freely in sugared drinks. The urine then 

 contained a mere trace of urea. After the patient had been 

 properly dieted for some time, I obtained the urine for the 

 second analysis, which in its results differs very little from the 

 first. Eight days from this time I again analysed it, and found 

 that the sugar had almost entirely disappeared. 



About three months afterwards I received some more of his 

 urine for analysis ; it was then very rich in sugar, while urea 

 was present to only a very small amount. Albumen was only 

 detected in the urine of the first analysis. Uric acid was always 

 present, but only in very small quantity. 



1 Journ. fiir prakt. Chem. vol. 6, p. 114. 



