URINE. 319 



Syphilis. 



[Heller examined the urine of a man aged 38 years, who was 

 taking iodide of potassium for a syphilitic eruption accompa- 

 nied with pains in the bones. When the urine was first 

 examined he was taking two scruples daily in three ounces of 

 distilled water ; on the second occasion (four days afterwards) 

 he was taking additionally half a grain of iodine. 



1. 2. 



Specific gravity . . 1015 1021 



Water . . . 974-800 954-40 



Solid constituents . . 25'200 45-60 



Urea . . . 7736 13-82 



Uric acid . . . 0-310 0-51 



Extractive matters and hvdrochlorate ) j o* 1 i * 



of ammonia ". . * 



Fixed salts, including iodide of potas- 1 i(V520 19-32 



The urine on the first occasion was excreted in about the 

 normal quantity, was of a dark-yellow colour, and had an acid 

 reaction : on the second occasion it was of an intensely dark- 

 yellow colour, and its reaction was faintly alkaline; its amount 

 was also diminished. No albumen or biliphaein was present in 

 either case. 



After the continuance of the second prescription for eight days, 

 the urine of twenty-four hours was collected with the view of 

 ascertaining the amount of iodine removed by the kidneys. 

 The whole daily urine amounted to 850 grammes or 24-5 

 ounces. 



In order to estimate the amount of iodine, 200 grammes of 

 urine were evaporated, the residue dissolved in water, and am- 

 monia added to the filtered solution till it exhibited a strongly 

 alkaline reaction. On the addition of nitrate of silver a preci- 

 pitate was thrown down which was washed with a weak solution 

 of ammonia, dried, and weighed. 



From the 200 grammes of urine 0-94 of iodide of silver were 

 obtained, containing 0-507 of iodine; hence 1000 parts of urine 

 contained 2*535 of iodine, corresponding to 3*322 of iodide of po- 

 tassium. Consequently, in the whole daily amount of urine there 

 were contained 2'824 grammes or 38-689 grains of the iodide. 



