URINE. 325 



acid were deposited. For several days he found as much as 

 half a drachm in six ounces of urine, or about 10 of hip- 

 puric acid in 1000 parts. It afterwards gradually diminished, 

 requiring considerable evaporation before crystals were depo- 

 sited, and ultimately disappeared. The patient had previously 

 suffered from voiding an excess of urea, and his urine had con- 

 tained a deposit of ammoniaco-magnesian phosphate. 



Dr. Pettinkoffer 1 has also published an analysis of urine con- 

 taining an excess of hippuric acid. The patient was a girl aged 

 13 years, suffering from chorea. The urine was limpid and 

 acid on emission, but soon became alkaline and deposited crystals 

 of ammoniaco-magnesian phosphate. After pouring nitric acid 

 on the evaporated alcoholic extract with a view of determining 

 the amount of urea, Dr. Pettinkoffer was surprised to find that 

 instead of the usual crystalline plates of nitrate of urea, brownish 

 yellow needles made their appearance. Under the microscope 

 the needles were found to be six-sided prisms, in some places 

 intermingled with plates of nitrate of urea. The urine evi- 

 dently contained a large amount of hippuric acid in combination 

 with potash or soda, from which the nitric acid separated it. 

 When the alcoholic extract of the urine was evaporated, mixed 

 with hydrochloric acid, and allowed to stand, four-sided pris- 

 matic crystals of hippuric acid were deposited. 



1000 parts of urine contained 40-668 of solid residue, of 

 which 31*251 were soluble in spirit, and consisted of hippurates, 

 urea, extractive matters, and chlorides ; while the remaining 

 9-417 were composed of urates, phosphates, and sulphates, to- 

 gether with mucus and water- extract. 



The solid residue yielded, on incineration, 10*599 of fixed 

 salts. 



On the following day, 1000 parts of urine yielded 49*825 of 

 solid residue and 12*985 of ash, consisting of: 



Carbonates of lime and magnesia . 1-153 1 



, 1 1-866 insoluble m water. 

 Earthy phosphates . . . 0-713 J 



Carbonate of soda . . . 3*996 



Chlorides of sodium and potassium . 6'181 



Phosphate of soda . . . 0-128 



Sulphate of lime . . .0-814 



1 Liebig's und Wohler's Annalen, vol. 50, No. 1. 



