APPENDIX. 515 



1st Case. A man of tolerably robust appearance, aged 

 38 years. The disease was somewhat advanced, and there was 

 considerable 03dema. The blood was analysed on two occa- 

 sions. On the first occasion it was taken by cupping from 

 the region of the kidney. It was very fluid but of the normal 

 colour. The clot was small and presented no peculiarity. The 

 serum was slightly coloured. Under the microscope the blood- 

 corpuscles appeared large and swollen. The blood was tested 

 for urea, and found to contain a considerable quantity. 



Five ounces were subsequently removed by venesection. The 

 colour of the blood on this occasion was rather dark, and the 

 coagulation was perfect. The clot was of a bright red colour 

 on the surface, but otherwise dark, and there was no buffy coat. 

 The serum was very pale and opalescent, and its specific gravity 

 was only 1022. It contained no bile-pigment, and its reaction 

 was strongly alkaline. 



In 1000 parts were contained : 



Water . . 805-39 



Solid constituents . 194-61 



Fibrin . . 3-52 



Albumen . 51-45"| 



Kcve S matter 8-15 S M d "< f "" 68 ' 15 



Urea . . l'85j 



Haematoglobulin . 122-94 



2d Case. A woman, aged about 30 years, with the disease 

 in an early stage. There was slight oedema of the feet and 

 face, accompanied with pain in the region of the kidneys. Four 

 ounces of blood taken from the arm presented no physical pe- 

 culiarities. The specific gravity of the serum was only 1018, 

 or 10 lighter than normal serum. The clot was to the serum 

 in the ratio of 544-75 : 455-25. 



In 1000 parts of blood there were contained : 

 Water . . . 816-04 



Solid constituents . . 183-96 



Fibrin . . . 2-66 



RxeTs^tf 111 * UttlC 6XtraCtiVe mattCr 4 6-9 6 1 S lid residue of m 

 Ur^a * '. '. - '. 1-74 J 56 ' 73 



Haematoglobulin . . 124-57 



Heller's general conclusions respecting the blood in Bright's 

 disease are that the specific gravity and the amount of solid 



