534 APPENDIX. 



The urine contained albumen, an extremely small quantity 

 of urea, and not a trace of either uric or hippuric acid. Hence 

 the acid reaction could not depend (as Liebig supposes) on those 

 acids, and Heller believes that " the acid reaction of this urine, 

 and, indeed, of the urine in Blight's disease generally, (where 

 uroxanthin is always present in large quantity,) and most pro- 

 bably of the normal secretion, (at least in part,) is dependent 

 on uroxanthin, which comports itself as an acid, being precipi- 

 table by metallic salts/' 



The body was examined two days after death. A small 

 quantity of urine, amounting to hardly a drachm, was found in 

 the bladder. It had much the same properties as the urine 

 removed by the catheter before death : it had the same acid 

 reaction, and the same yellow colour. It deposited a copious sedi- 

 ment, consisting for the most part of pavement epithelium, and 

 the characteristic cylinders ; it likewise contained mucus- corpus- 

 cles and oil-globules. The urine contained uroxanthin, but 

 not a trace of uroglaucin or urrhodin, which were, however, 

 subsequently obtained, both by nitric acid and by exposure to 

 the atmosphere. 



f. A man under the care of Dr. Seibert. The disease was 

 of considerable standing, and had assumed a chronic form. 

 There was much oedema of the feet, extending to the body, 

 and the secretion of urine was diminished. The urine was of 

 a pale wine-yellow colour, turbid, and threw down a slight 

 deposit consisting of pavement epithelium, cylinders, mucus- 

 corpuscles, and crystals of ammoniaco-magnesian phosphate. 



It was faintly alkaline and rapidly developed ammonia ; its 

 specific gravity was 1014. Nitric and hydrochloric acids com- 

 municated a reddish violet tint to it. After a time albumen 

 f with a violet tint was precipitated ; hence the urine contained 

 uroxanthin. 



In 1000 parts there were contained : 



Water . . . . . 969-25 



Solid constituents . . . . 30-75 



Urea . . . . . 2-50 



Uric acid . . . . 0-60 



Albumen .... 6'25 

 Extractive matters, uroxanthin, and carbonate of ammonia 17' 70 



Fixed salts 3-50 



The fixed salts consisted for the most part of phosphate of 



