APPENDIX. 537 



the early stages but likewise towards the close of the disease. 

 In the former case it arises from congestion, in the latter it is 

 a consequence of incipient dissolution. 



i. A woman aged 40 years, with much oedema, under the 

 care of Dr. Sterz. 



The urine, in this case, was very remarkable for its ex- 

 tremely high specific gravity, dependent on an enormous 

 amount of albumen. The secretion was very much diminished. 

 The urine was of a clay-yellow colour, turbid, and formed a 

 tolerably abundant sediment, containing numerous cylinders 

 and mucus-corpuscles, together with urate of ammonia. There 

 were also a few granular cells (Gluge's inflammatory globules) 

 and numerous albuminous fungi. 



The reaction of the urine was acid. Nitric acid caused a 

 dense coagulation of albumen, which rapidly assumed a violet 

 tint ; hence a tolerably large amount of uroxanthin was like- 

 wise present. The specific gravity was 1047. 



In 1000 parts there were contained : 



Water . . . .860 



Solid constituents . . . 140 



Albumen . . . .57 



The urine retained these characters for a considerable time, 

 always holding hsematin in solution. It subsequently became 

 less dense, as the disease assumed a chronic character. 



k. A girl aged ten years : oedema general and well-marked. 

 The urine was very pale, and of a dirty clay-yellow colour ; a little 

 fluid fat separated on the surface. There was a very slight de- 

 posit of epithelium and albuminous fungi. Reaction faintly 

 acid; specific gravity 1005. A small quantity of albumen was 

 present, which, on being precipitated by nitric acid, rapidly 

 assumed a violet tint ; on the addition of hydrochloric acid the 

 urine was rendered turbid, and likewise became of a violet 

 colour ; a relatively increased quantity of uric acid was thus 

 separated, and the crystals were of a beautiful deep blue tint. 

 Hence, notwithstanding the low specific gravity, the urine con- 

 tained a large amount of uroxanthin. Of urea there were only 

 traces, and the salts were diminished to an extreme degree ; the 

 phosphate of soda the principal ingredient being far below 

 the average, the sulphates and chloride of sodium very trifling, 



