THE ANIMAL PARASITES OF MAN 



by their diminutive size (length 15 p, breadth 10 //,). The case com- 

 municated by Grunow may also possibly refer to Isospora bigemina. 1 



FIG. 75. Isospora bigemina, Stiles (from the intestine of a dog), a, Piece of an intestinal 

 villus beset with Isospora, slightly enlarged ; d, Isospora bigemina (15 /j. in diameter), shortly 

 before division ; c, divided ; d, each portion encysted forming two spores ; e, four sporozoites 

 in each part, on the left seen in optical section, together with a residual body highly magnified. 

 (After Stiles.) 



Roundish or oval structures of 6 yu, to 13 yu- in diameter occurred in the 

 mucous membrane of the gut. and in the fceces of a case of enteritis. 



DOUBTFUL SPECIES. 



In literature many other statements are found as to the occurrence of 

 Coccidia-like organisms in different diseases of man. In some of the cases the 

 parasites proved to be fungi. This was the case with the parasites of a severe 

 skin disease of man, formerly called Coccidioides immitis and Coccidioides pyogenes. 

 Other statements are founded on misapprehensions, or are still much disputed. 

 If reference is here made to " Eimeria hominis" R. Blanchard, 1895, this 

 is done on the authority of the investigator mentioned. The structures in 

 question are nucleated spindle-shaped bodies of very different lengths (18 /j. 

 to 100 /*) which either occurred isolated or were enclosed in large globular or 

 oval cysts, alone or with a larger tuberculated body ("residual body"). These 

 formations were found by J. Kiinstler and A. Pitres in the pleural exudation removed 

 from a man by tapping. The man was employed on the ships plying between 

 Bordeaux and the Senegal River. 



Blanchard looks upon the fusiform bodies as merozoites and the cysts as 

 schizonts of a Coccidium. On the other hand, Moniez declares the spindle bodies 

 to be the ova and the supposed residual bodies to be " floating ovaries " of an 

 Echinorhynchus. 



Seven's "monocystid Gregarines," which were taken from the lung tissue of a 

 still-born child, are also quite problematical. 



No less doubtful are the bodies which Perroncito calls Coccidiutn jalinum, and 

 which he found in severe diseases of the intestine in human beings, pigs, and guinea- 

 pigs ; Borini also reported another case. 



1 Grunow, " Ein Fall von Protozoan (Coccidien?) Erkrankung des Darmes," Arch. f. 

 exper. Path, und Pharm., 1901, xlv, p. 262. 



