TRICHINELLA SPIRALTS 



425 



(3) Period of encystment : Symptoms of marked cachexia. Third 

 week : Second period of oedema, especially of face. Delirium, 

 somnolence, lung affections. Death or gradual subsidence of 

 symptoms in mild cases. 



Eosinophilia (50 per cent, or more) is present. 



In consequence of the new batches of young produced during several weeks, 

 the above-mentioned symptoms of disease are often considerably aggravated ; the 

 fever increases, delirium may arise, and infiltration of the lungs, fatty degeneration 

 of the liver and inflammation of the kidneys may ensue; the initial slight oedema 



A. 



c. 



FIG. 303. A., isolated muscular fibre of a rat, invaded by Trichinella. 510/1. ., 

 section through the muscle of a rat; the infected fibre has lost its transverse stiiation ; its 

 nuclei are enlarged and multiplied. 310/1. C., portion of a Trichinella capsule, at the pole 

 of which connective tissue cells are penetrating the thickened sarcolemma. (After Hertwig- 

 Graham.) 



may extend, the strength dwindles, and in many cases the patients succumb to the 

 trichinosis. In severe cases improvement of the condition is only apt to occur 

 in the fourth or fifth week ; the convalescence is always protracted. 



The muscular fibres attacked degenerate, the transverse striation 

 at first disappearing ; the fibres then assume a granular appearance, 

 the nuclei multiply and become enlarged, and are surrounded by an 

 area of granular material, which stains more deeply than the remaining 

 contents of the sarcolemma. Two or three weeks after infection, the 

 spirally rolled-up Trichinellae have grown to 0*8 to ro mm., and in 

 their vicinity the muscular fibre is swollen, spindle-shaped, and the 



