SUPPLEMENT 673 



Aspidium spinulosum and A. dilatatum, two fern roots indigenous to 

 Sweden, and obtained remarkable results (doses of 4 grm.). Lauren 1 

 had previously recorded similar results, and recently Friedjung, 2 

 using extr. aspid. spinulos. 



Cortex radicis granati as fresh bark is a very good drug, and is 

 usually given as a decoction : iSo'O bark to i,ooo'o water, boiled for 

 forty hours to 240-0, and a small cupful to be given every half an hour ; 

 colic, vomiting and diarrhoea, are, however, easily induced. The chief 

 constituent of the granate root, pelletierinum, possesses vermicidal 

 properties, and is much recommended, especially in France. Sequelae 

 easily arise (vertigo, hazy vision, malaise, vomiting, quickened heart's 

 action, muscular tremors, cramps in the calves), especially in delicate 

 persons and children, so that one should refrain from giving it to the 

 latter especially (Driven 3 ). Sometimes, judging by the experience of 

 Sobotta 4 and Boas, 5 the action is problematical. Where it is desired 

 to employ it in the case of adults, the following is prescribed : pellet, 

 sulfur. o'3 to 0*4 grm., acid, tannic. 0*5 grm., sir. rub. jd. 30*0 grm., to 

 be taken at one time, and a quarter to half an hour after a purgative 

 (senna infusion). In the case of children it is better to employ 

 semina cucurbitae maximae instead of extractum filicis maris. Sixty 

 to 100 pumpkin seeds are pounded up with sugar, which yield a 

 pleasant-tasting electuary, and which are taken all at once ; half an 

 hour afterwards a laxative is taken (Storch, 6 Pick 7 ). Jungklauss's 

 preparation is nothing else than a pumpkin extract ; its action is 

 favourable; it is, however, too expensive (Ritter 8 ). Flores kousso 

 up to 15 to 20 grm. in compressed form or in sugar or honey in the 

 form of electuaries (children 2-0 to 10*0 grm. according to age) is not to 

 be relied upon ; kussin, prepared from kousso flowers (Bedall, Munich), 

 is not a pure body ; when taken it is divided into four parts up to 

 ro to 2-0 grm. with elaeosaccharum menthae, at half-hourly intervals ; 

 it is said to be less unpleasant than treatment with flores kousso (Lieb- 

 reich and Langgard 9 ). Kosinum crystallisatum (dose 1-5 to 2*0 grm.) 

 is prepared by the firm of Merck. Kamala is the least potent of the 

 tapeworm drugs in use, and is principally to be recommended in the 

 treatment of children: 1-5 to 3-0 grm. in electuaries. According to 

 Leichtenstern 10 and White n chloroform, even in toxic doses, cannot 



1 Lauren, Thtrap. Monatsk., 1899. 

 < 2 Friedjung, Ges. f. innere Med., Wien, March 8, 1906. 



3 Drivon, Lyon mid., 1902. 4 Sobotta, loc. cit. 5 Boas, loc. cit. 



6 Storch, see Lenhartz, loc. cit. 



1 Pick, Ges.f. innere Med., Wien, March 8, 1906. 



8 Ritter, Frag. med. Wochenschr., 1904, v. 



9 Liebreich and Langgard, " Kompendium der Arzneiverordnung," 1907. 



10 Leichtenstern, " Therap. der Gegenwart," 1899. 



11 White, Scot. Med. and Surg. Journ., 1900. 



