APPENDIX ON PROTOZOOLOGY 737 



over the surface of the body towards the insertion of the anterior 

 flagellum. 



Another species, Cercomonas parva, has been found in cultures of 

 human faeces by Hartmann and Chagas 1 (1910). It has a somewhat 

 different structure. 



Furthur researches are necessary on the organisms variously 

 referred to the genus Cercomonas. 



Transmissive Phase of Trypanosomes in Vertebrates. In 

 addition to the general remarks on the morphology of trypanosomes 

 set forth on pp. 70 to 72, it may be noted that Woodcock 2 (November, 



1914) states that, in certain cases, there is a definite transmissive phase of 

 a trypanosome in its vertebrate host. He quotes the work of Minchin 

 and himself on T. noctuce of the little owl, in which the transmissive 

 form is spindle-shaped and occurs in the bird's peripheral blood 

 during the early summer months (see p. 69). A similar phase occurs 

 in T. Jringillarnm, and Robertson 3 has found that the short, stumpy 

 form of T. ganibiense is its transmissive phase in vertebrates. 



Trypanosoma lewisi (see p. 88). Brown (1914-15) has published 

 some interesting results on the potential pathogenicity of T. lewisi. 

 Blepharoplastless Trypanosomes (see p. 101). Laveran 4 (April, 



1915) suggested a practical use of strains of blepharoplastless trypano- 

 somes produced by the action of drugs. He finds that tryposafrol 

 will also produce such strains, and remarks on blepharoplastless 

 strains of T. evansi and T. brucei, which in the former case can 

 undergo 450 passages without reversion, and in the latter 273 

 passages. He states that if it is desired to inoculate surra or nagana 

 to Capridas or Bovidae in order to produce immunity, use should be 

 made of the blepharoplastless races of the respective trypanosomes, 

 which races are a little less virulent than the corresponding normal 

 ones. Also, the immunity which follows from an infection due to 

 blepharoplastless T. evansi or T, brucei is only a little less complete 

 than that following infections from either of the respective normal 

 strains. 



The Experimental Introduction of certain Insect Flagellates 

 into various Vertebrates, and its bearing on the Evolution of 

 Leishmaniasis. In continuation of the remarks on pp. 103, 104, 

 and 112, further researches have been conducted on the introduction 

 into vertebrates of flagellates normally parasitic in insects. The 

 vertebrates became infected by inoculation with the flagellates or by 



1 Mem. Inst. Oswalao Cruz, ii, p. 67. 



2 Arch. f. Protistenk., xxxv, p. 197. 



3 Proc. Roy. Soc. t B, Ixxxv, p. 527. 



4 C. R. Acad. Sti., clx, p. 543. 



